TransMolecular, Inc.: An Oncology Focused Biotechnology Company
 
Pursuing Cures for Cancer Through Targeted Therapy
   


metastatic brain tumors

glioma | other primary brain tumors | metastatic brain tumors


Metastatic brain tumors are the most common form of brain tumor. In U.S, alone, there are an estimated 98,000 to 170,000 new cases diagnosed each year.

Unlike primary brain tumors, metastatic brain tumors are tumors that spread to the brain from a different location in the body. The most common cancers associated with brain metastases are lung, colon, breast, and melanoma, as well as lymphoma. Most often, metastatic brain tumors occur in multiple areas of the brain, although some occur as solitary tumors.

Treatment for metastatic brain tumors varies based on the location and the number of tumors present. Surgery to remove some or all of the cancerous tissue, radiation, and/or radiosurgery are the standard methods for treatment. Clinical trials are currently being conducted to investigate the effects of chemotherapies and radiation enhancers in metastatic brain tumors. Overall, prognosis for metastatic brain tumors is poor. However, prognosis varies by primary tumor type and the location and number of tumor. For example, tumors arising from breast cancer are associated with a better prognosis than those arising from colon cancers. Likewise, patients with single tumors and few or no other metastases have longer median survival than patients with multiple tumors and/or metastases in other areas of the body.

For information about an ongoing clinical trial evaluating I-TM-601 in patients with recurrent or refractory metastatic tumors, click here.


Reference:
1. Adult Brain Tumors: Treatment (PDQ?). National Cancer Institute. Available at:
http://www.cancer.gov/cancertopics/pdq/treatment/adultbrain/healthprofessional. Accessed 8/06.

 

 

 

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